You are accessing a medical content website
Are you a health professional?

Revista Española de Cardiología (English Edition) Revista Española de Cardiología (English Edition)
Rev Esp Cardiol. 2018;71:95-104 - Vol. 71 Num.02 DOI: 10.1016/j.rec.2017.04.033

Trends in Hospitalization and Mortality Rates Due to Acute Cardiovascular Disease in Castile and León, 2001 to 2015

Juan B. López-Messa a,, Jesús M. Andrés-de Llano b, Laura López-Fernández a, Jesús García-Cruces c, Julio García-Crespo c, Miryam Prieto González a

a Servicio de Medicina Intensiva, Complejo Asistencial Universitario de Palencia, Palencia, Spain
b Unidad de Investigación, Complejo Asistencial Universitario de Palencia, Palencia, Spain
c Servicio de Medicina Preventiva, Complejo Asistencial Universitario de Palencia, Palencia, Spain

Refers to

Analysis of Hospitalization Trends for Heart Failure in the Health Registries of Different Autonomous Communities
María L. Fernández Gassó, Lauro Hernando-Arizaleta, Joaquín A. Palomar Rodríguez, Domingo A. Pascual-Figal
Rev Esp Cardiol. 2018;71:128-9
Full text - PDF


Cardiovascular disease. Myocardial infarction. Unstable angina. Heart failure. Acute ischemic stroke. Hospitalization. Mortality.


Introduction and objectives

To analyze hospitalization and mortality rates due to acute cardiovascular disease (ACVD).


We conducted a cross-sectional study of the hospital discharge database of Castile and León from 2001 to 2015, selecting patients with a principal discharge diagnosis of acute myocardial infarction (AMI), unstable angina, heart failure, or acute ischemic stroke (AIS). Trends in the rates of hospitalization/100 000 inhabitants/y and hospital mortality/1000 hospitalizations/y, overall and by sex, were studied by joinpoint regression analysis.


A total of 239 586 ACVD cases (AMI 55 004; unstable angina 15 406; heart failure 111 647; AIS 57 529) were studied. The following statistically significant trends were observed: hospitalization: ACVD, upward from 2001 to 2007 (5.14; 95%CI, 3.5-6.8; P < .005), downward from 2011 to 2015 (3.7; 95%CI, 1.0-6.4; P < .05); unstable angina, downward from 2001 to 2010 (–12.73; 95%CI, –14.8 to –10.6; P < .05); AMI, upward from 2001 to 2003 (15.6; 95%CI, 3.8-28.9; P < .05), downward from 2003 to 2015 (–1.20; 95%CI, –1.8 to –0.6; P < .05); heart failure, upward from 2001 to 2007 (10.70; 95%CI, 8.7-12.8; P < .05), upward from 2007 to 2015 (1.10; 95%CI, 0.1-2.1; P < .05); AIS, upward from 2001 to 2007 (4.44; 95%CI, 2.9-6.0; P < .05). Mortality rates: downward from 2001 to 2015 in ACVD (–1.16; 95%CI, –2.1 to –0.2; P < .05), AMI (–3.37, 95%CI, –4.4 to –2, 3, P < .05), heart failure (–1.25; 95%CI, –2.3 to –0.1; P < .05) and AIS (–1.78; 95%CI, –2.9 to –0.6; P < .05); unstable angina, upward from 2001 to 2007 (24.73; 95%CI, 14.2-36.2; P < .05).


The ACVD analyzed showed a rising trend in hospitalization rates from 2001 to 2015, which was especially marked for heart failure, and a decreasing trend in hospital mortality rates, which were similar in men and women. These data point to a stabilization and a decline in hospital mortality, attributable to established prevention measures.


You can access the full text of this article:

Members of the Spanish Society of Cardiology

Subscribers of Revista Española de Cardiología

You may purchase this article for 30.00 €

Buy Now
Subscribers of ScienceDirect

1885-5857/© 2018 Sociedad Española de Cardiología. Published by Elsevier España, S.L.U. All rights reserved